Uses of Sildenafil

Sildenafil is used to treat pulmonary arterial hypertension and to improve penile functions.

Therapeutic Category

Sildenafil: Phosphodiesterase type 5 (PDE 5) inhibitors

How Sildenafil works

Sildenafil works by blocking the effects of certain enzymes (PDE5) within the body which limits blood flow to the lungs and penis. As a result, it causes widening of blood vessels (arteries) supplying these organs, increases blood flow and oxygen supply and improves their functions.

Common side effects of Sildenafil

• headache
• flushing
• indigestion, diarrhoea
• pain in the arms or legs
• vision problems
• flu-like symptoms, inflammation of the sinuses, fluid retention
• difficulty in sleeping, anxiety, shaking
• sensation of pins and needles
• vertigo (spinning sensation)
• nosebleed, runny nose, cough, stuffy nose
• nausea, vomiting, stomach inflammation, heartburn, piles, abdominal distension, dry mouth, diarrhea
• hair loss
• skin redness, night sweats
• muscle pain, back pain
• increased erections

When to consult your doctor

Consult your doctor if you experience:

• prolonged or painful erection (priapism)
• sudden decline or loss of vision
• fits or seizures
• pneumonia, abnormal heartbeat, chest pain, fainting
• infections (viral infection of the gut, urinary tract infections and tooth cavities)
• fits, hearing impairment inflammation of digestive tract

Health Tips for Sildenafil

• Sildenafil is not suitable for use in women
• Sildenafil is generally more effective when taken on an empty stomach
• Avoid consumption of alcohol or grapefruit juice while taking Sildenafil as it may increase its side effects
• Avoid using recreational drugs (like amyl nitrate, etc.) while taking sildenafil as it may cause a dangerous drop in blood pressure
• Sildenafil should not be taken more than once in a 24-hour period
• Before taking Sildenafil, inform your doctor if you have any liver, kidney, or heart problems

AtaraInvasive Infections:

While Sildenafil is effective in treating conditions affecting the lungs and sinuses, it may not be suitable for you if you have, liver, or chronic kidney disease. Your doctor may want to talk to your doctor before taking this medication.

Health Conditions Sildenafil May Cause Liver Aneros>:

Your doctor may want to reduce the recommended dose of Sildenafil, if necessary. Tell your doctor if you have any health problems.

Safety Information

• Do not take Sildenafil if you are allergic to any of the components.
• Sildenafil is not for immediate use. For best results, take it as soon as 1 hour before a dose.
• Do not take it more often than once in a 24-hour period.
• If you have liver, kidney, or chronic kidney disease, talk to your doctor before taking it.
• Elderly patients in their 80s are more likely to experience side effects when taking Sildenafil.

Health Conditions:

Your doctor may sooner not take Sildenafil if you have liver, sinus, heart or airway problems, or a history of seizures. They may also need to monitor your progress.

Who Can Benefit from Sildenafil?

Sildenafil is one of the most effective medications used in the treatment of pulmonary arterial hypertension, also known as PADH.

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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

• The usual starting dose is 50mg, taken approximately one hour before sexual activity.
• Dosage can be adjusted depending on individual response and tolerability.
• Take only one tablet in 24 hours, with or without food.
• Avoid grapefruit juice, as it can increase the risk of side effects.
• A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

• Headache
• Flushing
• Nasal congestion
• Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

• Taking nitrates for chest pain
• With severe heart or liver conditions
• Under 18 years of age
• With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

• Nitrates
• Alpha-blockers
• Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

• Generic versions are more affordable than branded Viagra.
• Supplied by licensed UK pharmacies such as Online Chemist.
• Avoid counterfeit products from unregulated websites.

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Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.

Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.

consultation with doctor

Did you get an increase in blood pressure?

STEVE HAYS, HOST: with ED and PH?

someone who is eligiblesteve hay@----. hypertension.

oh my.

Yeah.

I take it with coffee and it keeps me up.

STEVE HAYS, YOUR CHILDREN:

it may also interact with certain medications.

STEVE HAYS, MATTERS?:

STEVE HAYS, IT REACH US:

this medicine may interact with certain medications.

this includes medications that are taken by mouth and may affect how Sildenafil works.

this includes medications that may interact with Sildenafil.

this includes medications that may affect how Sildenafil works.

itraconazole or ketoconazole may also affect how Sildenafil works.